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Participants were randomly assigned in a 1:1:1:1 ratio to receive once-daily oral Orforglipron (3 mg, 12 mg, or 36 mg) or Dapagliflozin 10 mg

Some of the studies showed a slight increase, some showed a slight decrease, but we were looking for statistical significance because if its not statistically significant, then I dont think you should act upon it, he said

Ming-Chiu O, Yi-Hsin Y, et al

350 SCFAs also play a role in regulating T cell differentiation to directly impact the inflammatory response within the central nervous system